Autonomous Reanimation and Evacuation (AREVA) Research Program

AREVA Logo

AREVA prioritizes translational research focusing on combat-relevant trauma and novel critical care interventions during care at ground level and high altitude, using a multi-disciplinary physician-led research team.

Mission: To enable research-to-practice translation of novel life-saving interventions in critical care via performance of clinically relevant translational trauma models followed by clinical trials.

Current Focus Area: Wearable medical solutions, polytrauma, critical care, extracorporeal life support (ECLS), autonomous integrated critical care systems for sustainment of life during ground and aeromedical manned and unmanned evacuation of critically ill.

Performance Capabilities

AREVA is an extramural research program and laboratory servicing nine combat casualty care-relevant research grants carried out at prolonged field-care intensive care unit studies for 72 hours. AREVA executes benchtop science and ex vivo experiments up to 6 hours duration in a dedicated plug-and-play circulation laboratory. AREVA performs large animal trauma studies with up to 72 hours of round-the-clock intensive care, conducted to human ICU standards of care. With a state-of-the-art coagulation laboratory and dedicated clinical diagnostic laboratory tools and point-of-care devices, AREVA can perform all phases of study from concept design through large animal experiments.

Current Projects

  • Clinically relevant realistic translational trauma models for testing of new treatments of trauma and single (lung, kidney, heart, brain) and multiorgan failure
  • Optimal management of patients with TBI and severe multisystem organ failure using novel forms of ECLS and treatment protocols
  • Development of blood friendly blood-polymer interfaces for heparin-free biologically friendly ECLS
  • Reduction in invasiveness and use of mechanical ventilation in respiratory failure of any kind using extracorporeal CO2 removal and oxygenation carried out in conjunction or instead of mechanical ventilation
  • Development of wearable critical care systems
  • Development of expeditionary and autonomous critical care solutions for life sustainment during care in place, evacuation delays for up to 72 hours, and manned and unmanned ground and aeromedical evacuation
  • Organ and limb perfusion systems
  • Animal Intensive Care Unit

    The animal intensive care unit is made of a fully self-enclosed space with dedicated HEPA filtration. It is equipped with state-of-the-art ICU patient care equipment to provide round-the-clock care to human standards of care. The Animal ICU is currently built to conduct two large animal experiments simultaneously, with plans for future expansion to 4 beds, including BSL 2 capability.

    LEARN MORE

    Unique Research Areas

    Early Post-Injury Point-of-Care ECLS

    AREVA is investigating earlier and wider applications of ECLS technologies in various configurations to improve patient outcomes.

    Examining blood sample in laboratory

    Anticoagulation Research

    AREVA tests ground-breaking ideas and approaches to limit or remove the anticoagulation and make biologically friendly interfaces suitable without the need to administer any anticlotting agents.

    Combat Casualty Care

    AREVA is committed to reducing mortality in combat casualties and civilian situations by examining the most severe non-survivable injuries.

    Selective Organ Perfusion

    AREVA applies ECLS therapy to organs and traumatically amputated limbs to enable a longer time before re-attachment. This novel work is conducted in a plug-and-play ex vivo circulation laboratory using donor blood.

    AREVA Collaborations

    AREVA has a strong record of successful collaborations with universities, companies, government agencies, clinical care teams, and industry leaders at all phases of research.

    Collaborate with AREVA

    Government

  • Uniformed Services University
  • U.S. Army Telemedicine and Advanced Technology Research Center
  • U.S. Special Operations Command
  • U.S. Army Institute for Chemical Defense
  • U.S. Army Institute of Surgical Research
  • Defense Health Agency
  • Food and Drug Administration
  • Academic

  • Harvard University and Mass General Hospital
  • University of Georgia
  • Colorado State University
  • University of the Incarnate Word
  • University of the Incarnate Word School of Osteopathic Medicine
  • University of Texas Health Science Center, San Antonio
  • University of Texas, San Antonio
  • University of California, Irvine, Beckman Laser Institute
  • University of South Florida, Tampa
  • COMMERCIAL & CLINICAL

  • Xenios/Fresenius
  • Maquet/Getinge
  • Cytosorb
  • Thornhill Medical
  • Pagonia Medical
  • Hamilton Medical
  • Draeger
  • Draeger STIMIT
  • Draper Labs
  • Methodist Hospital, San Antonio, TX
  • U.S. Army Burn Center, San Antonio
  • The AREVA Team

    Andriy Batchinsky, MD, Founder and Director, AREVA
    Teryn Roberts, PhD, Principal Investigator
    Yanyi Zang, PhD, Co-Investigator
    Daniel Wendorf, Laboratory Manager
    Brendan Beely, RRT, Research Coordinator
    George Harea, Research Associate

    Meet the Team

    Scientific Publications

    Geneva researchers at AREVA have published scientific publications in areas including Acute Respiratory Distress Syndrome (ARDS), Extracorporeal Life Support, Combat Care, Regenerative Medicine, Trauma Care, Wound Healing and more.

    Learn More