USU-4D Bio3 Center for Biotechnology

4D Bio3 is a Center for Biotechnology that develops and adapts promising new biotechnology for the benefit of Warfighter readiness and resilience. It champions a multidisciplinary approach that combines various Department of Defense (DOD), federal and non-federal experts across traditional and emerging fields.

Mission: To support and enhance the readiness, health, and well-being of America’s Warfighters, veterans, and their families by innovation, modernization, and translation of state-of-the-art biomedical technologies and services.

USU-4D Bio³

Mission Domains:
• Research and Engineering (TRL 1-4)
• Operationalization/Transition (TRL 4+)
• Education and Training

The center is based at the Uniformed Services University (USU) in Bethesda, Maryland and represents a collaboration between USU, Geneva, the Naval Research Laboratory, and Walter Reed National Military Medical Center. It includes a 10,000 sq. ft. multi-tool facility and supports a broad array of research and education applications. This facility includes a biofabrication suite, tissue culture room, bioreactor and sensor facility, and medical/surgical simulation room.

The capabilities present allow for military medical applications and translations to the fields of precision medicine, biomarker discovery, drug and vaccine development, medical technology validation, bio-sensors, environmental and occupational health, and regenerative medicine.

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Research Initiatives

• Warfighter Assessment of Readiness Needs (WARN)
• For Austere Military Environments (FAME)
• On-Demand Blood (ODB)
• Organ-On-Chip (OoC)
• Education and Training

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Learn more about 4D Bio3, its capabilities, and ways to get involved.

Core Capabilities

Additive Manufacturing wide assortment of 3D printers that support a variety of materials, including rigid & flexible components and conductive elements

Tissue Engineering bioprinting cell-laden inks and natural & synthetic scaffolding materials, electrospinning, patterning techniques

Cell Culture and Characterization equipment and expertise for culture of primary cells, stem cells, immortal lines

Bioreactor Design and Fabrication application-specific bioreactors including customized form factor and material selection

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COLLABORATE WITH US

4D Bio3 seeks like-minded research collaborators within the DoD, and with other federal, industry, and academic institutions.

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