Reproductive Health: Spermatogenic Stem Cell Culture Systems

Deadline
Multiple
OPPORTUNITY NO.
PAR-16-114
MECHANISM
R01
RESEARCH AREA(S)
SYNOPSIS

Spermatogenic Stem Cell Culture Systems to Preserve and Restore Reproductive Capacity in Males

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research in the area of spermatogenic stem cell (SSC) biology.  The overarching goal is to increase the chances that couples may have biological offspring without using conventional assisted reproductive modalities (i.e., IVF, ICSI).

A focal point of the initiative is on the development of new techniques to culture and expand these cells over an extended period of time.  Another area of study includes methods to eliminate malignant cells from SSC cultures following chemotherapy/radiation treatment. Also, spermatogenic stem cells from human adults could have a major impact on drug development and toxicity testing as animal-based systems do not sufficiently mirror the situation in humans.

Deadlines:
• Pre-Application Submission: 30 days before application submission due date
• Application Submission: 5:00 PM local time of applicant organization, June 5, 2016; June 5, 2017; June 5, 2018

 

ELIGIBILITY

Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.